PDRN (polydeoxyribonucleotide) is DNA extracted from salmon sperm cells. Clinical studies have indicated that PDRN can synthesise collagen, has anti-inflammatory and wound-healing properties, can treat hyperpigmentation, and boosts collagen.
Boots declared PDRN therapy as its number one trend to watch in 2025, and according to Gravel AI, there has been a remarkable growth in PDRN-containing products globally over the past six months by 108.4%. PDRN began its journey in clinical settings and dermatology in South Korea. In 2024, PDRN gained global attention as a science-backed ingredient, with its skin-repairing abilities capturing the interest of the beauty industry. An expert told Allure Magazine that PDRN is often used in injectables and treatments like microneedling or lasers, and it's now increasingly available in over-the-counter skincare.
PDRN Benefits:
- As PDRN becomes more popular in 2025 as a youth generation product for the skin, its ability to deliver visible results over time, improving the skin’s texture and elasticity and creating a gradient glow, has caught the attention of consumers.
- An expert from Vogue Beauty Arabia has highlighted that it’s gentle enough to be used with compromised or reactive skincare, helping to accelerate healing without causing additional irritation or disrupting the skin’s balance.
Korean skincare brands like Medicube, IOPE, and Genabelle are already using PDRN and vegan PDRN ingredients in their moisturisers, toners, and serums. In K-Beauty, PDRN is praised for its glass-like skin effects but more for its ability to strengthen and nourish the skin in the long run. According to Mintel, brands have started to combine PDRN in various facial skincare products, evidenced in the noticeable increase in APAC (Asia Pacific) between 2024 and 2025. PDRN is still considered a niche in the European market; looking forward, it will start to bridge the gap between professional and at-home skin products, making its benefits more accessible to consumers.
Surfachem offers: Actives from Kalichem
KaliGen is a yeast-derived, vegan-sourced PDRN nucleobiotic developed using BioNucleMax™ technology, delivering over 90% nucleic acid content. Using chicory as a fermentation substrate, it supports sustainable skin renewal, replumping, and revitalisation. Ideal for adaptive skincare targeting stress, recovery, and regeneration.
Kalinat AW Powder contains pure sodium DNA, suitable for anti-wrinkle and lifting treatments, as well as soothing medical applications. It helps improve skin thickness, stimulate collagen production, repair UV-induced damage, and counteract pollution-related stress.
Stimucap is a biotech active that targets hair loss and fibrosis by supporting follicle health and stem cell regeneration. It also promotes hair volumising and is suitable for use on the hair, beard, and eyelashes.
